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Insup Choi Selected Research

PTEN-induced putative kinase

2/2016PINK1 Deficiency Decreases Expression Levels of mir-326, mir-330, and mir-3099 during Brain Development and Neural Stem Cell Differentiation.
1/2016PINK1 expression increases during brain development and stem cell differentiation, and affects the development of GFAP-positive astrocytes.
2/2015PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death.
5/2013PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR.
3/2013PINK1 Deficiency Enhances Inflammatory Cytokine Release from Acutely Prepared Brain Slices.

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Insup Choi Research Topics

Disease

9Parkinson Disease (Parkinson's Disease)
01/2020 - 05/2013
2Neoplasms (Cancer)
01/2021 - 02/2016
2Gliosis
01/2020 - 04/2014
1Starvation
01/2021
1Parkinsonian Disorders (Parkinsonism)
11/2020
1Dementia (Dementias)
01/2020
1Cicatrix (Scar)
01/2020
1Synucleinopathies
01/2020
1Memory Disorders (Memory Loss)
11/2019
1Inflammation (Inflammations)
02/2016
1Mitochondrial Diseases (Mitochondrial Disease)
05/2013
1Encephalitis (Encephalitis, Rasmussen)
03/2013

Drug/Important Bio-Agent (IBA)

5PTEN-induced putative kinaseIBA
02/2016 - 03/2013
3Adenosine Triphosphate (ATP)IBA
01/2021 - 05/2013
2Glucose (Dextrose)FDA LinkGeneric
01/2021 - 05/2013
2Phosphotransferases (Kinase)IBA
01/2020 - 10/2016
2Leucine (L-Leucine)FDA Link
01/2020 - 10/2016
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2020
1Bevacizumab (Avastin)FDA Link
01/2020
1SynucleinsIBA
01/2020
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020
1Amyloid (Amyloid Fibrils)IBA
11/2019
1MicroRNAs (MicroRNA)IBA
02/2016
1UbiquitinIBA
01/2016
1Protein AggregatesIBA
01/2016
1Adenosine Diphosphate (ADP)IBA
09/2015
1Glial Fibrillary Acidic ProteinIBA
04/2014
1N-Methylaspartate (NMDA)IBA
04/2014
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2013
1p38 Mitogen-Activated Protein KinasesIBA
05/2013